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Null Formula DefenAge Skin Care System
- Development stage
- Unknown
- Lead developer
- DefenAge
- Modality
- Hydrogel Systems → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems
- Administration
- Topical
01
Overview
The Null Formula refers to the placebo or vehicle-controlled versions of the DefenAge Skin Care System, which were evaluated in clinical trials for the treatment of skin aging and photoaging. This system typically comprises three topical products: the 2-Minute Reveal Masque, the 24/7 Barrier Repair Cream, and the 8-in-1 BioSerum. Unlike the active DefenAge formulations, the Null Formula versions lack the proprietary MediCell Technology (MCT), which contains specific regenerative peptides known as defensins (specifically alpha-defensin 5 and beta-defensin 3). In clinical studies sponsored by Advanced Dermatology, the Null Formula serves as the comparative control to isolate the therapeutic effects of defensins on skin hydration, thickness, and the reduction of fine lines and wrinkles in aging skin.
- Brand names
- DefenAge Null Formula
- Other names
- Null Formula 2-Minute Reveal MasqueNull Formula 24/7 Barrier Repair CreamNull Formula 8-in-1 BioSerum
02
Targets
LGR6 (Leucine-rich repeat-containing G-protein coupled receptor 6)
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