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Number Ten
- Development stage
- Unknown
- Administration
- Oral
01
Overview
**Number Ten** is an orally administered multi-herb dietary supplement formulation investigated for obesity and weight loss. It is composed of rhubarb, ginger, astragalus, red sage, and turmeric. In a small randomized pilot study in healthy women with overweight or obesity, it did not produce meaningful weight loss at tolerable doses and caused dose-related loose stools. Chemical analysis identified sennosides, laxative constituents likely contributing to gastrointestinal toxicity, as well as rhein and gallic acid; no validated molecular target or clinically established anti-obesity mechanism has been demonstrated. ([nature.com](https://www.nature.com/articles/0803343))
- Other names
- NTNumber Ten
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