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Nuolitong

Development stage: Unknown
Lead developer: Beijing Plantai Pharmaceutical Technology Development
Modality: Small Molecules
Administration: Oral

Overview

Nuolitong is a Traditional Chinese Medicine (TCM) granule formulation developed by Beijing Plantai Pharmaceutical Technology Development Co., Ltd. specifically for the treatment of tension-type headaches. The formulation is designed to promote blood circulation and resolve blood stasis, addressing the underlying 'stasis' believed to cause pain in TCM theory. Its primary botanical ingredients include *Ligusticum chuanxiong* and *Curcuma longa*. Pharmacologically, components like tetramethylpyrazine from *Ligusticum chuanxiong* are known to exert vasodilatory and anti-inflammatory effects, which contribute to the relief of headache symptoms. Nuolitong has been approved in China for the management of tension-type headaches and is used to reduce the frequency and intensity of headache episodes.

Brand names: Nuolitong
Other names: Nuolitong Granules诺力通颗粒

Targets

CaV (Voltage-gated calcium channel protein complex)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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