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Nustem (DHNP-D01) is a veterinary cell therapy product developed by Daehan Nupharm, currently in Phase 3 clinical trials for the treatment of canine disc herniation and spinal cord injury. The therapy consists of adipose-derived mesenchymal stem cells (AD-MSCs), which are utilized for their regenerative, anti-inflammatory, and immunomodulatory properties. By secreting various growth factors and cytokines, Nustem aims to repair damaged neural tissues and alleviate the symptoms of intervertebral disc disease (IVDD) in dogs, potentially offering a therapeutic alternative to surgery. The product is designed as an off-the-shelf regenerative treatment to improve neurological function and quality of life in pets suffering from debilitating spinal conditions.
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