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Nutravestin
- Development stage
- Unknown
- Lead developer
- Intra Life
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Nutravestin (also known as Nutravestin-500) is an oral nutraceutical tablet developed by Intra Life, containing Univestin (UP446), a patented, standardized botanical blend of *Scutellaria baicalensis* (Chinese skullcap) root extract and *Acacia catechu* (black catechu) heartwood extract. It is formulated to alleviate joint pain, stiffness, and inflammation, and to support range of motion, flexibility, and physical function in individuals experiencing osteoarthritis-related discomfort. Nutravestin works through a multi-channel anti-inflammatory mechanism, primarily by inhibiting both cyclooxygenase (COX-1 and COX-2) and 5-lipoxygenase (5-LOX) enzymatic pathways, thereby reducing the production of pro-inflammatory prostaglandins and leukotrienes without the typical gastrointestinal side effects associated with traditional NSAIDs.
- Brand names
- NutravestinNutravestin-500Nutravestin500Nutravestin 500
- Other names
- Univestin
02
Targets
ALOX5 (Arachidonate 5-lipoxygenase)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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