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Nutrilarm (T1675) is an oral dietary supplement developed by Laboratoires Thea specifically for the management of dry eye syndrome. The formulation consists of a combination of omega-3 polyunsaturated fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and omega-6 polyunsaturated fatty acids, including gamma-linolenic acid (GLA) and linoleic acid (LA). These essential fatty acids act as precursors to anti-inflammatory mediators, helping to modulate the inflammatory processes on the ocular surface that characterize dry eye disease. Clinical evaluation in a Phase 2 trial demonstrated that Nutrilarm, when used as a 6-month dietary supplement, provides additional therapeutic benefits such as improved tear break-up time (TBUT) and reduced ocular fatigue in patients already receiving topical tear substitutes.
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