Nuvail

**Nuvail** (poly-ureaurethane 16% nail solution) is an FDA-approved prescription topical product developed by Innocutis for managing signs and symptoms of **nail dystrophy**, such as nail splitting, fragility, and brittleness in intact or damaged nails. It functions mechanically by forming a breathable, waterproof polymer film that adheres strongly to the nail surface, blocking water absorption to prevent the wet-dry cycle that causes damage, while allowing oxygen transfer and protecting against abrasion and friction. Applied daily before bedtime to clean nails, it supports nail plate strengthening without treating underlying infections like onychomycosis, though clinical studies showed improvements in nail parameters and fungal culture negativity.

Brand names

Nuvail

Other names

poly-ureaurethane