nux vomica extract

Nux vomica extract is a botanical preparation derived from the seeds of the *Strychnos nux-vomica* tree, primarily containing the alkaloids strychnine and brucine. Historically utilized as a central nervous system stimulant and tonic, its primary mechanism of action involves the competitive antagonism of glycine receptors in the spinal cord and brainstem, which leads to increased neuronal excitability. In modern clinical research, it is often studied in the context of toxicology, safety, or as a stimulant in healthy volunteer populations to assess physiological effects and potential for misuse, particularly in anti-doping studies.

Other names

Strychnos nux-vomica extractpoison nut extractquaker button extractstrychnine seed extract