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NVA1501-16 is a preclinical-stage small molecule developed by Novassay that targets the alpha-2/delta-1 (α2δ-1) subunit of voltage-gated calcium channels. This subunit is a well-established target for the treatment of neuropathic pain, as it modulates the trafficking and function of calcium channels involved in pain signaling. NVA1501-16 is being investigated for its potential in treating neuropathic pain and solid tumors, where α2δ-1 may play a role in cancer cell proliferation or tumor-associated pain management.
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