NVN4100

NVN4100 is an investigational **topical nitric oxide-releasing antimicrobial** product candidate from **Novan** for **companion animal health**. It is described as a new chemical entity derived from Novan's NITRICIL nitric oxide platform and is being explored primarily for **canine pyoderma** and potentially other veterinary dermatologic and otic bacterial infections. Preclinical data indicate inhibitory and bactericidal activity against pathogens relevant to animal skin and ear disease, including *Escherichia coli*, *Pseudomonas aeruginosa*, *Staphylococcus pseudintermedius*, and *Staphylococcus schleiferi*, including antimicrobial-resistant and susceptible strains. The precise chemical structure and finalized commercial formulation have not been publicly disclosed.