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NVP-1704

Development stage: Unknown
Lead developer: NVP Healthcare
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

NVP-1704 is a psychobiotic formulation developed by NVP Healthcare (Navipharm), consisting of a specific combination of two bacterial strains: *Lactobacillus plantarum* NK51 and *Bifidobacterium longum* NK46. It is designed to alleviate symptoms of stress, anxiety, and depression by modulating the gut-brain axis. The product has received approval from the South Korean Ministry of Food and Drug Safety (MFDS) as a functional health ingredient for improving mental health and stress-related fatigue. Clinical studies have demonstrated that NVP-1704 can reduce serum cortisol levels, improve sleep quality, and balance gut microbiota composition, which in turn influences neurotrophic factors and systemic inflammatory pathways associated with the stress response.

Other names: Lactobacillus plantarum NK51 and Bifidobacterium longum NK46 combinationNK51 + NK46

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