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Nvzhen Granule is a Traditional Chinese Medicine (TCM) product developed by Shandong Phoenix Pharmaceutical for the treatment of chronic insomnia. It is specifically formulated for patients presenting with the TCM pattern of liver–kidney yin deficiency and hyperactivity of heart–liver fire. The formulation typically contains extracts from botanical sources such as *Ligustrum lucidum* (Nvzhenzi), which is traditionally used in Chinese medicine to nourish the liver and kidneys. Nvzhen Granule is currently being evaluated in Phase II clinical trials in China to assess its efficacy on subjective sleep quality and objective polysomnographic (PSG) parameters, as well as its impact on traditional TCM symptom scores over an 8-week treatment period.
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