Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
NY-ESO-1
- Development stage
- Phase 1
- Lead developer
- GSK
- Modality
- Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
- Administration
- Intramuscular, Subcutaneous
01
Overview
NY-ESO-1 is a cancer-testis antigen, a protein expressed in a variety of tumors, including melanoma, synovial sarcoma, and multiple myeloma, but generally not in normal adult tissues, with the exception of testis and placenta. Its restricted expression pattern and demonstrated immunogenicity make it an attractive target for cancer immunotherapy. It is utilized in vaccine formulations to induce antigen-specific humoral and cellular immune responses, and as a target for T-cell receptor (TCR) engineered T-cell therapies, where T cells are genetically modified to recognize and attack NY-ESO-1-expressing cancer cells.
- Other names
- New York Esophageal squamous cell carcinoma-1
02
Targets
NY-ESO-1–MHC (New York esophageal squamous cell carcinoma 1 peptide–Major Histocompatibility Complex (NY-ESO-1 peptide–MHC))NY-ESO-1 (New york esophageal squamous cell carcinoma 1)
Beyond the preview
Go deeper on NY-ESO-1.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on NY-ESO-1.