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N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide

Development stage
Unknown
Modality
Small Molecules
01

Overview

N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide is a synthetic small molecule belonging to the biphenyl and sulfonamide chemical classes. It has been studied as an experimental compound, with no current approved indications or clinical use. The compound has been structurally characterized in protein-ligand complexes, notably in studies involving matrix metalloproteinases (MMPs), suggesting it may act as an inhibitor of these enzymes. However, there are no published clinical trials or marketed products containing this molecule[1][4][5]. Its mechanism of action is presumed to involve inhibition of MMP activity via chelation at the active site zinc ion, but this remains to be fully validated.

Other names
N-hydroxy-2-[2-hydroxyethyl-(4-phenylphenyl)sulfonylamino]acetamide
02

Targets

MMP2 (Matrix metalloproteinase-2)

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