oat beta-glucan + beta-glucanase

Oat beta-glucan + beta-glucanase is a combination of a soluble dietary fiber (oat beta-glucan, derived from the endosperm of oat kernels) and the enzyme beta-glucanase, which hydrolyzes beta-glucan[2][3]. Oat beta-glucan is well-established for its cholesterol-lowering and prebiotic properties, and has regulatory recognition for cardiovascular risk reduction[2]. Beta-glucanase enzymatic treatment breaks down β-glucan polymers into shorter oligomers, improving their fermentability by gut microbiota, enhancing both prebiotic and immunomodulatory effects, especially notable in infant gut models and dendritic cell activation[3]. The combination is primarily investigated as a functional food ingredient or supplement, especially for improving digestive health, immune function, and metabolic parameters via both fiber action and enzymatic modification[1][3]. Mechanistically, oat beta-glucan acts by increasing gut viscosity, interfering with nutrient absorption and binding bile acids, thereby reducing cholesterol absorption[1][2]. Beta-glucanase increases the solubility and fermentability of beta-glucan, leading to greater production of short-chain fatty acids and enhanced immune signaling through Dectin-1 activation[3].

Other names

oat beta-glucan and beta-glucanase