Drug intelligence / Profile preview

OB-24-02

Development stage
Preclinical
Lead developer
OCMS Bio
01

Overview

OB-24-02 is a preclinical therapeutic candidate developed by OCMS Bio for the treatment of human metabolism disorders. The drug targets the activin receptor type IIA and IIB (ActRIIA/B), which are members of the transforming growth factor-beta (TGF-beta) receptor family. These receptors play a significant role in regulating muscle mass, bone density, and metabolic homeostasis by binding ligands such as activins, myostatin, and growth differentiation factors. By modulating ActRIIA/B signaling, OB-24-02 is intended to address metabolic dysfunction, potentially through the enhancement of lean body mass or the regulation of energy expenditure.

02

Targets

ACVR2A (Activin receptor type 2A)ACVR2B (Activin receptor type IIB)

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