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OB101

Development stage: Preclinical
Lead developer: Shenzhen Zero-One Life Technology
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

OB101 is an oral live biotherapeutic product (LBP) being developed by Shenzhen 01 Life Technology Co., Ltd (01Life) for the treatment of obesity. As a microbiome-based therapy, it consists of live microorganisms intended to provide a therapeutic effect by modulating the host's gut microbiota and metabolic processes. The program is currently in the IND-enabling stage of development, aiming to address weight management through the restoration or modification of the intestinal microbiome.

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