Drug intelligence / Profile preview

OBT542

Development stage
Preclinical
Lead developer
Oxford BioTherapeutics
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

OBT542 is an investigational antibody-drug conjugate (ADC) being developed by Oxford BioTherapeutics for the treatment of cancer. As an ADC, it is designed to utilize a monoclonal antibody to specifically target an antigen expressed on tumor cells, delivering a potent cytotoxic payload directly to the site of the disease while minimizing systemic toxicity. The drug was identified using Oxford BioTherapeutics' proprietary OGAP® (Oxford Genome Anatomy Project) database, which integrates proteomic and genomic data to discover novel tumor-associated antigens. As of early 2024, the specific biological target and the nature of the cytotoxic payload remain undisclosed, and the program is in the discovery stage of development.

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