Drug intelligence / Profile preview

OC-001

Development stage
Phase 2
Lead developer
Ocellaris Pharma
Modality
Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

OC-001 is an experimental immunotherapy drug being developed for the treatment of locally advanced or metastatic solid tumors, including a range of cancers such as renal cell carcinoma, non-small cell lung cancer, ovarian cancer, bladder cancer, sarcoma, triple negative breast cancer, and others. It is a monoclonal antibody that targets tumor necrosis factor (TNF), acting as a TNF inhibitor to prevent inflammation and potentially enhance anti-cancer immune responses. OC-001 is being evaluated both as monotherapy and in combination with PD-L1 inhibitors (such as avelumab) in ongoing phase 1/2 clinical trials. The drug is administered intravenously[1][2][3][5].

02

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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