Drug intelligence / Profile preview

Ocean Univ. of China HDAC3 compound 9c

Development stage
Preclinical
Lead developer
Ocean University of China
01

Overview

Ocean Univ. of China HDAC3 compound 9c: sourced facts only. name: "9c shows a selectivity of 71 fold for HDAC3 over HDAC1 and can significantly inhibit the proliferation activity of MV4-11 cells in vitro." [PMID:39047608]; target: "9c shows a selectivity of 71 fold for HDAC3 over HDAC1 and can significantly inhibit the proliferation activity of MV4-11 cells in vitro." [PMID:39047608]; developer: "Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, 266003, China." [PMID:39047608]; stage: "Furthermore, when combined with Venetoclax, 9c can effectively induce apoptosis in MV4-11 cells in vitro and reduce the expression of anti-apoptotic proteins" [PMID:39047608]

02

Targets

HDAC3 (Histone Deacetylase 3)

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