Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Ocean Univ. of China HDAC3 compound B22
- Development stage
- Preclinical
- Lead developer
- Ocean University of China
- Modality
- PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules
01
Overview
Ocean Univ. of China HDAC3 compound B22: sourced facts only. name: "Among these, representative compound B22 potently degraded HDAC3, with a DC50 of 30.73 nM and a Dmax of 82%." [PMID:41610583]; target: "Among these, representative compound B22 potently degraded HDAC3, with a DC50 of 30.73 nM and a Dmax of 82%." [PMID:41610583]; developer: "Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao 266003, China." [PMID:41610583]; modality: "In this study, we designed a series of novel HDAC3 PROTACs based on our previously designed HDAC3 inhibitor as the POI ligand." [PMID:41610583]; stage: "B22 synergized with the clinically approved AML agent Venetoclax, demonstrating potent anti-proliferative effects and significantly promoting apoptosis in MV4-11 cells." [PMID:41610583]
02
Targets
HDAC3 (Histone Deacetylase 3)
Beyond the preview
Go deeper on Ocean Univ. of China HDAC3 compound B22.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Ocean Univ. of China HDAC3 compound B22.