Drug intelligence / Profile preview

Ocean Univ. of China NLRP3 compound 19

Development stage
Unknown
Lead developer
Ocean University of China
01

Overview

Ocean Univ. of China NLRP3 compound 19: sourced facts only. name: "Mechanistic studies indicated that compound 19 directly targets the NLRP3 protein (KD: 0.45 μM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis." [PMID:39317006]; target: "Mechanistic studies indicated that compound 19 directly targets the NLRP3 protein (KD: 0.45 μM), blocking the assembly and activation of the NLRP3 inflammasome, leading to anti-inflammatory effects and inhibition of cellular pyroptosis." [PMID:39317006]; developer: "Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao 266003, China." [PMID:39317006]

02

Targets

NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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