Ocean Univ. of China NLRP3 compound H28

Ocean Univ. of China NLRP3 compound H28: sourced facts only. name: "Preliminary mechanistic studies have revealed that compound H28 exhibits direct binding to the NLRP3 protein (KD: 1.15 μM), effectively inhibiting the assembly and activation of the NLRP3 inflammasome." [PMID:38492493]; target: "Preliminary mechanistic studies have revealed that compound H28 exhibits direct binding to the NLRP3 protein (KD: 1.15 μM), effectively inhibiting the assembly and activation of the NLRP3 inflammasome." [PMID:38492493]; developer: "Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao 266003, China." [PMID:38492493]; modality: "Targeting the NLRP3 protein with small molecule inhibitors shows immense potential as an effective strategy for disease intervention." [PMID:38492493]; stage: "The results in a mouse acute peritonitis model revealed that H28 effectively inhibit the NLRP3 inflammasome pathway, demonstrating their anti-inflammatory properties." [PMID:38492493]