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OCNR-101 is a preclinical-stage small molecule drug candidate being developed by Onconic Therapeutics for the treatment of solid tumors. It is designed as a synthetic lethality-based DNA damage response (DDR) pathway inhibitor, specifically targeting a novel mechanism to overcome resistance in patients who have developed resistance to conventional PARP (poly ADP-ribose polymerase) inhibitors. The drug is currently in the candidate discovery and lead optimization phase.
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