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octenidine dihydrochloride + isopropyl alcohol (Becton Dickinson)
- Development stage
- Unknown
- Lead developer
- Becton Dickinson
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
OCT-tinted is an investigational preoperative skin antiseptic developed by Becton, Dickinson and Company (BD). It is a combination of octenidine dihydrochloride, a bispyridinamine antiseptic, and isopropyl alcohol (IPA), formulated with an added colorant to facilitate visual confirmation of skin coverage during application. The product is designed to prevent surgical site infections (SSIs) by providing broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and multidrug-resistant strains. It is delivered via a single-use applicator. In a randomized, triple-masked Phase 2 clinical trial (NCT03224299), OCT-tinted was evaluated for its effectiveness in preoperative skin preparation compared to an active control (ChloraPrep) and a negative control (saline) in healthy volunteers.
- Other names
- OCT tintedoctenidine tinted formulation
02
Targets
Microbial cytoplasmic membrane lipid bilayer
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