Drug intelligence / Profile preview

Ocufolin Forte

Development stage
Preclinical
Lead developer
Aprofol
Modality
Small Molecules
Administration
Oral
01

Overview

Ocufolin Forte is an innovative folate-based dietary supplement classified as a Food for Special Medical Purposes (FSMP), developed by the Swiss life science company Aprofol AG. Its primary active ingredient is L-methylfolate (levomefolic acid), which is delivered within a lipophilic matrix that also contains essential minerals and antioxidants. The product is specifically designed to address ocular vascular diseases by targeting elevated homocysteine (Hcy) levels and increased retinal venous pressure (RVP), both of which are significant risk factors for vision loss. Ocufolin Forte is primarily indicated for age-related macular degeneration (AMD), including neovascular AMD (nAMD), and has been investigated for its potential benefits in glaucoma and diabetic retinopathy. Clinical evidence suggests that it supports improvements in retinal microcirculation and total retinal blood flow, particularly when used as an adjunct to standard anti-VEGF therapies.

Brand names
Ocufolin Forte
Other names
Ocufolin forte
02

Targets

ET (Endothelin receptors)NOS3 (eNOS)

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