Drug intelligence / Profile preview

Ocuvite Duo

Development stage
Unknown
Lead developer
Bausch + Lomb
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Ocuvite Duo is a multi-ingredient nutritional supplement developed by Bausch + Lomb specifically designed to support eye health and mitigate the progression of age-related macular degeneration (AMD). The formulation typically includes a combination of the carotenoids lutein and zeaxanthin, omega-3 fatty acids (DHA and EPA), antioxidant vitamins (C and E), and essential minerals (Zinc and Copper). These components work synergistically to increase macular pigment optical density (MPOD), filter high-energy blue light, and neutralize reactive oxygen species within the retina. Clinical studies, such as the LUTEGA trial, have investigated its effects on retinal function using multifocal electroretinography (mfERG) and its ability to replenish essential nutrients that naturally deplete with age.

Brand names
Ocuvite DuoOcuvite
Other names
Ocuvite Lutein & Omega-3
02

Targets

STARD3 (StAR-related lipid transfer domain protein 3)Misfolded SOD1GSTP1 (Glutathione S-transferase P)

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