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ODC-TARGET A
- Development stage
- Preclinical
- Lead developer
- Boehringer Ingelheim
- Modality
- Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
01
Overview
ODC-TARGET A is an investigational antibody-drug conjugate (ADC) being developed by Trutino Biosciences, a subsidiary of Boehringer Ingelheim. The drug is designed for the treatment of solid tumors and utilizes Trutino's proprietary On-Demand Cytokine (ODC) platform technology. This platform employs a masking strategy intended to restrict the drug's activity to the tumor microenvironment, thereby potentially reducing systemic side effects and improving the therapeutic window. While the ODC platform is primarily associated with cytokine therapies, ODC-TARGET A applies this conditional activation mechanism to an ADC architecture. The specific antigen targeted by the antibody component, referred to as "Target A," remains undisclosed in public pipeline documentation. The program is currently in the IND-enabling stage of development.
- Other names
- ODC-Target A
02
Targets
Cr (Chromium)
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