Drug intelligence / Profile preview

ODC-TARGET E

Development stage
Preclinical
Lead developer
Trutino Biosciences
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

ODC-TARGET E is a preclinical-stage antibody-drug conjugate (ADC) being developed by Trutino Biosciences for the treatment of autoimmune diseases. The drug is designed to target a specific, undisclosed biological entity referred to as Target E, delivering a therapeutic payload with high precision to modulate immune responses. This program represents an expansion of Trutino's portfolio beyond its core On-Demand Cytokine (ODC) platform into the ADC space for immunological indications. By leveraging the ADC modality, the program aims to provide targeted therapy that improves efficacy while minimizing the systemic side effects often associated with traditional immunosuppressive agents.

02

Targets

SELE (E-selectin)

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