Drug intelligence / Profile preview

OJL332

Development stage
Preclinical
Lead developer
Bausch + Lomb
Modality
Small Molecules
Administration
Topical Ophthalmic
01

Overview

OJL332 is a second-generation, small molecule antagonist of the transient receptor potential vanilloid 1 (TRPV1) receptor, also known as the vanilloid receptor. It is in preclinical development as a potential therapy for ocular surface diseases, likely targeting chronic ocular surface pain or related indications. OJL332 was initially developed by Bausch & Lomb, later held by Novartis, and as of 2023 acquired by Bausch + Lomb.

Other names
OJL332OJL-332OJL 332
02

Targets

TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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