Drug intelligence / Profile preview

OKSI (Universitas Negeri Semarang)

Development stage
Phase 3
Lead developer
Universitas Negeri Semarang
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

OKSI is a botanical combination extract developed by Universitas Negeri Semarang, Indonesia, specifically formulated to mitigate exercise-induced oxidative stress. The product contains a mixture of 400 mg of Garcinia mangostana (mangosteen) rind extract and 200 mg of Solanum lycopersicum fructus (tomato) extract. It leverages the antioxidant properties of bioactive compounds such as xanthones and anthocyanins from mangosteen, alongside lycopene and other antioxidants from tomato. OKSI is primarily intended for sedentary individuals to reduce biomarkers of oxidative damage and cardiac stress, specifically targeting levels of malondialdehyde (MDA) and high-sensitivity Cardiac-Troponin I (hs-cTnI) following physical exertion. It is registered as a traditional medicine in Indonesia.

Brand names
OKSI
Other names
Garcinia mangostana rind and Solanum lycopersicum fructus extractGarcinia-mangostana-L-rind and Solanum-Lycopersicum-Fructus mixture-extractmangosteen and tomato extract

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