Drug intelligence / Profile preview

Oligen

Development stage
Unknown
Lead developer
Oleolive
Modality
Small Molecules
Administration
Oral
01

Overview

Oligen is a commercialized dietary supplement ingredient developed through an exclusive partnership between Oleolive and Applied Food Sciences (AFS). It is a standardized olive polyphenol extract concentrated in two key bioactive compounds: oleocanthal and oleacein, which are naturally found in trace amounts in extra virgin olive oil. Oligen functions primarily as a Cyclooxygenase-2 (COX-2) inhibitor, supporting a healthy inflammatory response and providing antioxidant benefits. It is marketed for applications in joint health, cardiovascular support, and healthy aging/longevity. The ingredient is typically administered orally in capsule, tablet, or softgel form, with a standard 400mg dose delivering the polyphenol equivalent of approximately one-quarter cup of premium olive oil. Oligen utilizes proprietary extraction technology to ensure high bioavailability without the need for additional absorption enhancers.

Brand names
Oligen
Other names
Oligen-Oleoliveolive polyphenol extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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