Drug intelligence / Profile preview

oligomaltose

Development stage
Preclinical
Modality
Small Molecules
Administration
Topical
01

Overview

Oligomaltose is a type of oligosaccharide, a carbohydrate composed of a few saccharide units. In the context of the provided clinical trial, it is an active ingredient in a skin care ointment being studied for its efficacy in controlling eczema pruritus. While the exact chemical structure of "oligomaltose" can vary, it is often related to isomaltooligosaccharides (IMOs), which are glucose oligomers with α-D-(1,6)-linkages. Oligosaccharides, particularly those with prebiotic properties, are known to interact with the skin microbiome, promoting the growth of beneficial bacteria and inhibiting pathogenic ones. This modulation of the microbiome contributes to improved skin barrier function, reduced inflammation, and overall skin health. Beyond topical applications, IMOs are also widely used as dietary supplements and functional food ingredients due to their prebiotic effects on gut health, low glycemic index, and anti-caries properties.

Other names
Oligomaltose X

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