Drug intelligence / Profile preview

OlyCAR-019

Development stage
Phase 2
Lead developer
People's Liberation Army
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

OlyCAR-019 is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy developed by the 920th Hospital of Joint Logistics Support Force of the People's Liberation Army of China. The therapy is manufactured using the OlyCAR platform, a novel system designed to generate clinical-grade CAR-T cells in a significantly reduced timeframe compared to traditional methods. OlyCAR-019 specifically targets CD19, a B-lymphocyte antigen expressed on the surface of most B-cell malignancies. It is currently being evaluated in Phase 1/2 clinical trials for the treatment of relapsed or refractory B-cell malignancies, including B-cell leukemia and B-cell lymphoma, where it is administered via intravenous infusion to induce targeted cytotoxicity against malignant B-cells.

Other names
Anti-CD19 Autologous CAR-T Cell InfusionAnti-CD-19 Autologous CAR-T Cell InfusionAnti-CD 19 Autologous CAR-T Cell InfusionAnti-CD19 CAR-T Manufactured by OlyCAR PlatformAnti-CD-19 CAR-T Manufactured by OlyCAR PlatformAnti-CD 19 CAR-T Manufactured by OlyCAR Platform
02

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