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omega 3 fatty acid + fish oil + monacoline + mevacolin
- Development stage
- Preclinical
- Lead developer
- Mogon Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
omega 3 fatty acid + fish oil + monacoline + mevacolin is a preclinical-stage small-molecule combination drug being developed by Mogon Pharmaceuticals for the management of dyslipidemia and cholesterol lowering. The drug is administered orally via a liquid improved modified oral-release capsule. It utilizes a dual mechanism of action: the fish oil/omega-3 fatty acid component provides lipid modulation, while the monacolin (also known as mevacolin or monacolin K) component acts as an HMG-CoA reductase inhibitor, the same biological target as statin drugs. This combination is intended to reduce LDL cholesterol and triglycerides while increasing HDL cholesterol levels, providing a comprehensive approach to lipid management through both enzymatic inhibition of cholesterol biosynthesis and fatty acid-mediated lipid regulation.
- Other names
- Omega-3 fatty acid fish oilOmega3 fatty acid fish oilOmega 3 fatty acid fish oilMonacolineMevacolinMonacolin KLovastatin
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)FFAR4 (Free fatty acid receptor 4)PPARG (Peroxisome proliferator-activated receptor gamma)
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