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Omega-3 Fatty Acid Ethyl Ester 90 Soft Capsules
- Development stage
- Unknown
- Lead developer
- BASF
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Omega-3 Fatty Acid Ethyl Ester 90 Soft Capsules is a pharmaceutical-grade omega-3 fatty acid formulation developed and marketed by Jiangsu Wangao Pharmaceuticals in China. The product contains a high concentration (at least 90%) of eicosapentaenoic acid (EPA) ethyl ester and docosahexaenoic acid (DHA) ethyl ester derived from fish oil. It is indicated for the treatment of hypertriglyceridemia and the promotion of cardiovascular health. The mechanism of action involves the reduction of hepatic triglyceride synthesis, likely through the inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase (DGAT) and the activation of peroxisome proliferator-activated receptor alpha (PPAR-alpha), which enhances fatty acid oxidation. This leads to decreased secretion of very-low-density lipoprotein (VLDL) and a subsequent reduction in plasma triglyceride levels.
- Brand names
- Omega-3 Fatty Acid Ethyl Ester 90 Soft CapsulesOmega3 Fatty Acid Ethyl Ester 90 Soft CapsulesOmega 3 Fatty Acid Ethyl Ester 90 Soft Capsulesω-3脂肪酸乙酯90软胶囊
- Other names
- eicosapentaenoic acid ethyl ester + docosahexaenoic acid ethyl esterEPA/DHA ethyl esters
02
Targets
PPARA (Peroxisome proliferator-activated receptor alpha)DGAT1 (Diacylglycerol O-acyltransferase 1)
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