omega-3 fatty acids + folic acid

The combination of **omega-3 fatty acids** and **folic acid** (Vitamin B9) is an investigational therapeutic regimen developed by the **Reproductive Partners Medical Group** for the treatment of male infertility. This specific formulation was evaluated in a Phase 2 clinical trial (NCT01548625) to assess its impact on sperm quality parameters—including concentration, motility, and morphology—as well as sexual function in infertile men. Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential structural components of the sperm cell membrane; their incorporation is thought to enhance membrane fluidity and protect against oxidative damage. Folic acid serves as a critical cofactor in one-carbon metabolism, facilitating DNA synthesis and repair during spermatogenesis and helping to regulate homocysteine levels, which are often elevated in cases of subfertility.

Other names

Omega 3 and Folic AcidOmega3 and Folic AcidOmega-3 and Folic Acid