Drug intelligence / Profile preview

Omega-3 plus

Development stage
Unknown
Lead developer
Mansoura University
Modality
Small Molecules
Administration
Oral
01

Overview

Omega-3 plus is an oral dietary supplement containing omega-3 polyunsaturated fatty acids (n-3 PUFAs) that is being investigated by Mansoura University for its chemopreventive properties in patients with high-risk non-muscle invasive bladder cancer (NMIBC). In the clinical trial NCT04664816, it is administered at a dose of 1200 mg twice daily for at least 12 months following transurethral resection of bladder tumor (TURBT) and in conjunction with intravesical Bacillus Calmette-Guérin (BCG) immunotherapy. The treatment is hypothesized to reduce the risk of cancer recurrence by modulating inflammatory pathways and molecular markers within the bladder tissue, which are being analyzed through histopathological and molecular studies of resected urothelial tissues.

Brand names
Omega-3 plusOmega3 plusOmega 3 plus
Other names
o-Mansoura University-non-muscle invasive bladder canceromega-3 polyunsaturated fatty acidsomega3 polyunsaturated fatty acidsomega 3 polyunsaturated fatty acidsn-3 PUFAsn3 PUFAsn 3 PUFAsn-3PUFAsn3PUFAsn 3PUFAs
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)NF-κBFFAR4 (Free fatty acid receptor 4)

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