Drug intelligence / Profile preview

OmegaD

Development stage
Phase 3
Lead developer
OmegaD
Modality
Small Molecules
Administration
Oral
01

Overview

**OmegaD** is an oral softgel nutraceutical product developed by OmegaD for dry eye disease. Its active constituents are the marine omega-3 fatty acids **eicosapentaenoic acid** and **docosahexaenoic acid** in triglyceride form. The product was evaluated in randomized, double-masked, placebo-controlled Phase 3 studies in dry eye disease, with mineral-oil softgels used as placebo. The development rationale was to increase systemic omega-3 fatty-acid exposure relative to omega-6 fatty acids and thereby modulate inflammatory processes relevant to ocular-surface disease and meibomian gland dysfunction.

Brand names
OmegaD
Other names
OmegaD softgels
02

Targets

DGAT1 (Diacylglycerol O-acyltransferase 1)SREBP-1 / SREBF1 (SREBP-1)PAP (Prostatic acid phosphatase)

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