Drug intelligence / Profile preview

OmniCART

Development stage
Preclinical
Lead developer
MicroCrispr
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

OmniCART is an allogeneic chimeric antigen receptor (CAR) T-cell therapy being developed by MicroCrispr for the treatment of various solid tumors. As an allogeneic or off-the-shelf therapy, it utilizes T-cells derived from healthy donors rather than the patients themselves, which are then genetically modified to target specific cancer cells. The platform is designed to address multiple indications, including lung, prostate, breast, oral, and brain cancers. Currently in the preclinical stage, OmniCART aims to overcome the limitations of autologous CAR-T therapies, such as high manufacturing costs and long lead times, by providing a readily available therapeutic option for cancer patients.

02

Targets

MAGEA8 (Melanoma-associated antigen 8)

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