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Oncobax AK

Development stage: Unknown
Lead developer: EverImmune
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Vaccines & Immunotherapeutics
Administration: Oral

Overview

Oncobax AK is a live biotherapeutic product (LBP) containing a proprietary strain of Akkermansia muciniphila (strain P2261). It is designed to be used as an oral adjuvant to anticancer immunotherapies, specifically to boost the immune system and restore sensitivity to immunotherapies in patients with primary resistance. The drug works by modulating the gut microbiota of cancer patients who are deficient in Akkermansia and resistant to immunotherapy treatments.

Brand names: Oncobax AK
Other names: Oncobax-AK

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