Drug intelligence / Profile preview

oncoxin

Development stage
Unknown
Lead developer
Laboratorios Catalysis
Modality
Recombinant Proteins and Enzymes, Peptides, Small Molecules
Administration
Oral
01

Overview

Oncoxin is a multicomponent nutritional supplement primarily used as an adjunct in cancer patients undergoing chemotherapy or radiotherapy to manage complications such as oral mucositis and improve quality of life. Formulated with vitamins, amino acids, microelements, and biologically active substances of natural origin, it includes antioxidant and anti-inflammatory compounds like epigallocatechin gallate (EGCG) from green tea extract, and other plant extracts with antitumoral properties. Oncoxin exerts broad-spectrum antioxidant effects; it slows tumor cell proliferation by inducing cell cycle arrest (notably at G2/M phase), promotes apoptosis via upregulation of pro-apoptotic proteins (such as p53 and Bax), inhibits angiogenesis by blocking growth factor signaling pathways (including VEGF), suppresses matrix metalloproteinases involved in tumor invasion/metastasis, and modulates immune responses by stimulating interferon production. Laboratorios Catalysis is the developer and manufacturer. Clinical studies suggest it can reduce the severity of oral mucositis during cancer therapy and may enhance the efficacy or tolerability of standard oncological treatments.

Brand names
OncoxinOcoxinOcoxin Oral SolutionOncoxin-Viusid
02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)MMP9 (Matrix metalloproteinase-9)MMP2 (Matrix metalloproteinase-2)

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