Drug intelligence / Profile preview

Onfyte

Development stage
Unknown
Lead developer
Percos
Modality
Small Molecules
Administration
Topical
01

Overview

Onfyte (also marketed as Onfyte Lotion) is a multi-action topical veterinary formulation developed by Percos India under its Aranex Animal Health division for the treatment of mixed dermatological infections in companion animals, including dogs and cats. The lotion is co-formulated with five active ingredients: clobetasol propionate (a potent corticosteroid that reduces inflammation and itching), ofloxacin and neomycin sulphate (broad-spectrum antibiotics targeting bacterial pathogens), miconazole nitrate (an antifungal agent active against yeasts and dermatophytes), and zinc sulphate (which acts as a soothing agent and promotes wound healing). Onfyte is primarily indicated for eczematous dermatosis complicated by bacterial and fungal infections, otitis externa, pyoderma, ringworm, and infected external wounds.

Brand names
OnfyteOnfyte Lotion
Other names
clobetasol propionate + miconazole nitrate + neomycin sulphate + ofloxacin + zinc sulphate
02

Targets

Bacterial RibosomeDNA gyraseTopo IV (Bacterial Topoisomerase IV)GR (Glucocorticoid receptor)CYP51A1 (Sterol 14α-demethylase)

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