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ONO-1110
- Development stage
- Phase 2
- Lead developer
- Ono Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
ONO-1110 is a small molecule drug developed by Ono Pharmaceutical for the treatment of pain-related conditions. It acts as an endocannabinoid regulator, specifically modulating cannabinoid receptors, but with a mechanism distinct from exogenous cannabinoids like marijuana. This design aims to harness the beneficial pharmacological effects of cannabinoids (such as analgesia and mood regulation) while minimizing central side effects like euphoria and somnolence that are associated with cannabis-derived drugs. ONO-1110 is being investigated in Phase II clinical trials for several indications including fibromyalgia, Hunner type interstitial cystitis, major depressive disorder, postherpetic neuralgia, social anxiety disorder, generalized anxiety disorder, myofascial pain syndromes, and phobia (social). The drug is administered orally[1][2][3][4][6].
- Other names
- ONO 1110ONO1110ONO-1110
02
Targets
CB (Cannabinoid receptors)
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