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Opti-Free Express No Rub MPS
- Development stage
- Unknown
- Lead developer
- Alcon
- Modality
- Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
Opti-Free Express No Rub MPS is a multipurpose disinfecting solution (MPDS) for soft contact lenses, originally developed and manufactured by Alcon. It features a dual-disinfectant system consisting of Polyquad (polyquaternium-1) and Aldox (myristamidopropyldimethylamine). Polyquad is a large-molecule quaternary ammonium germicide that minimizes uptake into the lens matrix, while Aldox is a biocidal agent effective against fungi and protozoa like Acanthamoeba. The formulation includes citrate and Tetronic 1304 to facilitate cleaning and protein removal, allowing for a "no rub" regimen where lenses are cleaned and disinfected through soaking alone. Innovative Medical has utilized this solution as a reference standard in Phase 4 clinical trials to evaluate the performance of new lens care products.
- Brand names
- Opti-Free ExpressOpti-Free Express No Rub Multipurpose Disinfecting Solution
- Other names
- Opti-Free Express No Rub MPS
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