Drug intelligence / Profile preview

Optive Fusion + Optive Gel Drop

Development stage
Unknown
Lead developer
AbbVie
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Optive Fusion + Optive Gel Drop is a combination of two ophthalmic lubricants used to treat and relieve symptoms of moderate to severe dry eye disease. Optive Fusion contains carboxymethylcellulose sodium (CMC), glycerin, and sodium hyaluronate. CMC and sodium hyaluronate act as ocular lubricants while providing osmoprotective and moisturizing effects for the corneal surface; glycerin further enhances hydration and protection[1][2][5]. The drops restore osmotic balance and promote longer-lasting comfort for dry, irritated, or fatigued eyes, and are compatible with contact lens use. Optive Gel Drop features a higher concentration of carboxymethylcellulose sodium (1%), resulting in a gel-like consistency for prolonged lubrication and protection against further irritation, particularly for severe, persistent dry eye symptoms[4][6][7]. It shares osmoprotectant benefits with Optive Fusion and can be combined for additive/synergistic effect. Both products utilize Purite (stabilized oxychloro complex) as a gentle preservative which breaks down into natural tear components on the eye, minimizing irritation[1][5][8]. Developed primarily for dry eye, burning, irritation, and discomfort due to dryness or environmental factors[9].

Brand names
Refresh Optive FusionRefresh Optive Gel Drops
Other names
Optive Fusion UDRefresh Optive Fusion UD

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