Drug intelligence / Profile preview

Opulus-P

Development stage
Phase 4
Lead developer
Sapient Laboratories
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Opulus-P is an ophthalmic fixed-dose combination solution developed and marketed by Sapient Laboratories. It contains phenylephrine (5% w/v), a selective alpha-1 adrenergic receptor agonist, and tropicamide (0.8% w/v), an anticholinergic muscarinic receptor antagonist. Together, these active ingredients act synergistically to induce rapid and temporary pupil dilation (mydriasis) and paralysis of the ciliary muscle (cycloplegia). Opulus-P is primarily indicated for diagnostic eye examinations, such as fundoscopy and retinal evaluation, as well as for preoperative preparation in ophthalmic surgeries where pupil dilation is required.

Brand names
Opulus-P
Other names
Opulus Pphenylephrine + tropicamidetropicamide + phenylephrine
02

Targets

ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)M1 (Muscarinic acetylcholine receptor M1)CHRM2 (M2)CHRM3 (M3)CHRM4 (M4)CHRM5 (M5)

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