Drug intelligence / Profile preview

OQR300

Development stage
Preclinical
Lead developer
OncoQr
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular, Subcutaneous
01

Overview

OQR300 is a preclinical-stage therapeutic cancer vaccine being developed by the Austrian biotechnology company OncoQR ML GmbH. The drug is built upon the proprietary S-TIR™ (Specific Total Immune Remodeler) platform, which is designed to induce high-titer, specific antibody responses against clinically validated targets by bypassing immune tolerance. The S-TIR™ technology utilizes a modular design consisting of a generic 'warhead' module to activate the immune system and a disease-specific 'immunogen' module. While OncoQR describes the target of OQR300 as a '3rd blockbuster-clinically validated target,' the specific molecular target and the primary cancer indication have not been publicly disclosed.

02

Targets

FCGR2B (Fc gamma receptor IIB)BCR (Immunoglobulin G B Cell Receptor)TLR9 (Toll-like receptor 9)FCGR2A (Low affinity immunoglobulin gamma Fc receptor II-a)

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