Drug intelligence / Profile preview

Orabro Gel

Development stage
Unknown
Lead developer
Canbro Healthcare
Modality
Small Molecules
Administration
Topical
01

Overview

Orabro Gel is a topical combination gel developed by Canbro Healthcare for the temporary relief of pain, inflammation, and discomfort associated with mouth ulcers, gum irritation, and denture-related soreness. It is formulated with three active ingredients: choline salicylate (8.7%), a nonsteroidal anti-inflammatory drug (NSAID) that reduces localized inflammation and pain by inhibiting cyclooxygenase (COX) enzymes; lignocaine hydrochloride (2.0%), a local anesthetic that provides rapid, localized numbing by blocking voltage-gated sodium channels; and benzalkonium chloride (0.01%), an antiseptic that helps maintain oral hygiene and prevent secondary microbial infections. Orabro Gel is applied directly to the affected oral mucosa to provide fast-acting relief.

Brand names
Orabro Gel
Other names
choline salicylate + lidocaine + benzalkonium chloridecholine salicylate + lidocaine hydrochloride + benzalkonium chloridecholine salicylate + lignocaine + benzalkonium chloridecholine salicylate + lignocaine hydrochloride + benzalkonium chloride
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NaV (Voltage-gated sodium channels)

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