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The oral electrolyte-carbohydrate nutrition supplement is a specialized nutritional intervention developed and studied by West China Hospital of Sichuan University, particularly within the framework of Enhanced Recovery After Surgery (ERAS) protocols for patients undergoing total knee arthroplasty (TKA) for knee osteoarthritis (gonarthritis). The supplement typically consists of a high concentration of complex carbohydrates (such as maltodextrin) and essential electrolytes (sodium, potassium, chloride). Its primary mechanism of action involves providing a preoperative carbohydrate load that shifts the patient from a fasted to a postprandial metabolic state, thereby stimulating insulin secretion and attenuating the surgical stress response. This helps to reduce preoperative discomfort (thirst, hunger, anxiety) and minimize postoperative insulin resistance, which is a key factor in accelerating functional recovery and reducing hospital stay duration.
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